Translation is the synthesis of a polypeptide using the information in the mRNA. During this stage, there is a change in language: The cell must translate the nucleotide sequence of an mRNA molecule into the amino acid sequence of a polypeptide. The sites of translation are ribosomes, molecular complexes that facilitate the orderly linking of amino acids into polypeptide chains.
Transcription is the synthesis (production) of RNA using information in the DNA. The two nucleic acids are written in different forms of the same language, and the information is simply transcribed, or “rewritten,” from DNA to RNA.
Watson and Crick’s model predicts that when a double helix replicates, each of the two daughter molecules will have one old strand, from the parental molecule, and one newly made strand.
The elegant double-helical structure of deoxyribonucleic acid (DNA) shook the scientific world when it was proposed in April 1953 by James Watson and Francis Crick. The DNA you inherited from your parents contains all your genes—your genetic information.
Chromosomal inheritance can result in mutations that increase genetic diversity but can also cause genetic disorders. Sexual reproduction can increase genetic diversity by creating offspring with extra or missing chromosomes.
In the 1900s, geneticists extended Mendelian principles not only to diverse organisms, but also to patterns of inheritance more complex than those described by Mendel.