1.4 Protein

Proteins are all constructed from the same set of 20 amino acids, linked in unbranched polymers. The bond between amino acids is called a peptide bond, so a polymer of amino acids is called a polypeptide. A protein is a biologically functional molecule made up of one or more polypeptides, each folded and coiled into a specific threedimensional structure.

To Think About:

What is the directionality of the subunits of Proteins? What are the four elements of protein structure? How may a change in the subunits of a protein lead to changes in structure or function?


Watch: AP Daily Video Protein

Answer the Following Questions:

  • To which functional group are new amino acids added when forming peptide bonds?
  • Complete this table:
Level Protein StructureDefinitionWhich bonds or forces cause this level of structure to form?
Primary  
Secondary  
Tertiary  
Quatenary  
  • How do the R-groups on amino acids influence protein folding?
  • How would substituting a polar amino acid for a nonpolar amino acid affect a protein’s structure and function?

Supplementary Resources:

  • Bozeman Science: Mr. Andersen’s “Proteins” video

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